Native type II collagen-induced arthritis in the rat. III. Relationship between the cellular immune response to native type II collagen and arthritis.
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منابع مشابه
Native type II collagen-induced arthritis in the rat. II. Relationship between the humoral immune response to native type II collagen and arthritis.
The onset of arthritis in Sprague-Dawley rats occurred between 10-13 days after intradermal injection of collagen when serum IgM and IgG antibody levels to native type II collagen had reached high levels. Although arthritis could be induced in rats immunized with 25-500 microgram native type II collagen in incomplete Freund's adjuvant, higher serum IgM and IgG antibody levels to native type II ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1983
ISSN: 0003-4967
DOI: 10.1136/ard.42.3.331